Understanding Allograft Cartilage Transplants

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Articular cartilage is a firm rubbery tissue that covers the ends of bones. It provides a smooth gliding surface for joints and acts as a cushion between bones.Cartilage can break down due to overuse or injury. This can lead to pain and swelling and problems with your joint.

Your treatment will depend on the size of the defect and the judgment of your surgeon. This procedure is performed on people who have a specific cartilage defect typically due to an injury. It is not done when cartilage loss is much more extensive.

A plug of allograft tissue containing bone and cartilage is shaped to fit into the area that is damaged. The damaged area is prepared and the new plug is inserted into the site.

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JRF Ortho specializes in providing orthopedic surgeons with the highest viability, most widely available cartilage solutions in the industry. Our goal is to provide innovative solutions for allograft joint repair to orthopedic surgeons who specialize in helping patients regain movement and improve their quality of life; thus, JRF Ortho is redefining the standard for allograft joint repair and maximizing the gift of donation.

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Benefits of allograft tissue transplants outweigh risks

Patients need not be afraid of receiving musculoskeletal allograft tissue transplants, but doctors have a responsibility to seek grafts from tissue banks that follow best known practices, such as those accredited by the American Association of Tissue Banks (AATB), said Gary E. Friedlaender, MD, at a Thursday afternoon media briefing on the topic of allograft safety.

“The risks from allografts are low and the benefits are impressively high,” said Dr. Friedlaender, chair of the department of orthopaedics and rehabilitation at the Yale University School of Medicine and chair of the AAOS Tissue Banking Project Team. “More than 800,000 grafts are performed in the United States each year, with few complications.”

Learn more about Allograft tissue transplants at JRF Ortho


“Allografts are most frequently used to accomplish bone fusions, improve the quality of bone in revision hip and knee replacement procedures, restore bone lost during injury or following removal of tumors, and promote the healing of fractures,” Dr. Friedlaender, explained.

The use of an allograft eliminates the need for a second surgery site to recover an autograft – a graft taken from the recipient’s own body – as well as the need to sacrifice a normal structure in one place for use in another location.

“This reduces the potential for complications arising from having an additional surgical procedure, and thereby results in less blood loss, less pain and a quicker recovery time,” he added.


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Meniscal Transplant in Patients 50 and Younger Relieves Pain, Delays Additional Surgery

By JRF Ortho

Most patients younger than age 50 with a torn or severely damaged meniscus experienced reduced pain and improved knee function following transplant surgery, according to a study in the latest issue of the Journal of Bone and Joint Surgery (JBJS). However, many patients required additional surgery within 10 years.

The meniscus is a wedge-shaped piece of fibrocartilage in the knee that acts as a shock absorber between the thighbone and shinbone. A meniscus can be torn during sports or wear away over time as the body ages. For younger patients with knee pain after loss of the meniscus, a meniscus transplant is performed to maintain a cushion between the two bones, stabilize the joint, prevent persistent knee pain, and to allow for greater mobility. An orthopaedic surgeon executes the knee surgery by using an arthroscope to accurately place and stitch new, transplanted meniscal tissue.

Researchers followed 38 meniscal transplant patients under age 50, who did not have arthritis, for an average of 11 years following surgery. Patient outcomes were evaluated based on clinical, subjective, and radiographic measures.

Click here to read the entire article>>

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JRF Ortho to Reach More Patients in Need of Fresh, “Living” Cartilage

OneLegacy, the nation’s largest organ, eye and tissue procurement organization, has expanded its reach of helping more people lead healthier lives through its new commitment to provide fresh, “living” cartilage to the nonprofit JRF Ortho. This cartilage, which can be used by surgeons throughout the world, will allow more people to walk and will allow young athletes to more easily continue to pursue their passion.

“There is an incredible need for fresh tissue from young donors that can be placed in the knee, ankle or other joints of waiting patients to dramatically improve movement and quality of life,” said Diane Wilson, chairman of the board of JRF Ortho. “Thankfully OneLegacy has stepped up to meet this challenge, and because of them we can expect to see superior clinical results and even more positive patient outcomes from those we serve.”

Fresh tissue—that which is not frozen or embedded in preservatives—can be used to replace and repair defects in articulating joints or torn or damaged meniscus. In many cases fresh grafts allow mobility that couldn’t be accomplished with alternate grafts or prostheses. The challenge is that these live, living cells need to be transplanted within 28 days of processing; and few organizations have been able to make the commitment to achieve that high standard. Now OneLegacy has.

Click here to read the entire press release..

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